Stienberg
re direct by Walgren :
Murray did not act like he was ACLS certified.
Propofol given in NY : it was in hospital settings
Gastro dentist ER doctors who use propofol : they receive appropriate training , trained staff and equipment are necessary
Article about the study in Taiwain : published in 2010, was an experimental study. The patients were given propofol in a hospital , with the appropriate equipment, the experiment was approved by their ethical comittee. They obtained written consents from the patients. 8 hours of fasting prior to being given propofol, propofol was given by an anaethesiologist. No other benzos were used. So what CM was doing was essentially an experiment.
Assume that dr Murray gave only 25mg, that there was no drip. Would you draw the same conclusions ? Yes
Was it a foreseeable risk that the patient could go into respiratory deperession and cardiac arrest ? Yes
Do you think CM caused MJ's death ? Yes
re cross by Flanagan
Did that study showed propofol helped insomnia : yes
in this case you need to analyse if the deviations from standard of care directly impacted MJ's death : yes.
Did the lack of back up battery lead to MJ's death ? No, but the other 5 deviations did;
CM gave propofol for 45 days without problems, so you're assuming things. Answer : no I didn't asume that he gave propofol, that he didn't have the equipment, the delay in calling 911, improper care during the arrest.
Dr Kaimangar : Pulmonary critical care and sleep medecine physician, UCLA medical center
direct examination Walgren
board certified : internal medicine, pulmonary medecine, critical care, sleep medecine.
Medical reviewer for the Cali Medical Board , assessed CM's care to MJ for the medical board.
Is propofol used in critical care unit : yes, daily.
Are you trained in using propofol : Yes. Propool is used for placement of endotracheal tubes, and for people on breathing machines. Propofol is the most commonly used drug for this.
What is your training for using of propofol ? You need to be well prepared for an emergency, It's necessary to be aware of the potential problems that could happen . Propofol is not used on unstable patients.
Is the staff trained : yes, there is a special training for using propofol. If there is no none especially trained for propofol, they call an anesthesiologist.
the continuum of sedation : there is a fine line between moderate sedation to deep sedation and to general anesthesia (not responsive to painful stimulation). It's difficult to predict how the patient will react.
When propofol is used , who is present ? For induction : an intensivist or an anesthesiolgist and a nurse, and respiratory therapist (except in extreme emergency the respiratory therapist might not have to time to come)
what is the monitoring equipment you need for propool: EKG machine, blood pressure (every 2 to 3 minutes), pulse oxymeter with an alarm, capnometer (for patients under ventilation, measures carbon dyoxide )
About CM's care of MJ : found multiple deviations of standard of care :
1 propofol given in an unacceptable setting : using this deep sedation agent in a home setting is unconceivable.
2 ACLS certified : the persons who gives propofol must be trained in ACLS and airways management. There is a risk of hypoventilation, and obstruction of the airway.
3 Need of assistance : CM needed a a second person to monitor, especially if you're going to leave the room. That goes withot saying
4 Pre procedure setup : imperative to be prepared for possible consequences. Things can change very quickly. A patient may look good, and the next minute there's a problem. You need a suction catheter, because patients can regurgitate into their airway, and block the airway, this can cause death. A crash cart (medication on hand : adrenaline, epehdrine, medication to correct the heart beat, etc...) , defibrilator, automated infusion pump (precise dosing for propofol) even with people who are intubated;
Theses are extreme deviation of standard of care = gross negligence.
Have you ever seen someone giving propofol at home in such settings : no, and would not have expected to see that.
5 Charts / medical documentation : or medical history, reactions to a medication. For example a blood pressure can look normal, but not be normal for a particular patient. And that change in blood pressure could be the indication of a problem.
6 : MJ was left alone : that is really not acceptable. Espacially since CM didn't have the right equipment.
7 Use of benzos : using lorazepam and midazolam on top of propofol can have higher effects : more significant respiratory depression, decrease cardiac output (often a consequence of resiratory depression), decreased blood pressure.
Cardiac arrest can occur directly, or because of low levels of oxygens.
8 dehydration : blood circulation is not good when you are dehydrated , causes low blood pressure. Benzos and propofol would also lower blood prossure . You should not use benzos or propofol if the patient is dehydrated.
9 failure to call 911 : 911 should have been called immediatey
10 improper CPR : if there was a pulse , the problem was breathing. CM should have dealt with airway management .
CPR was ineffective : was not on a hard surface, doing it with one hand was ineffective. If you do CPR correctly, you just allow about 20% of the normal blood circulation, so if you do it incorrrectly ...
break